Shared requirement for MYC upstream super-enhancer region in tissue regeneration and cancer
I. K. Sur, W. Zhao, J. Zhang, M. Kling Pilstrom, B. Rozell, A. Webb, H. Cheng, A. Ristimaki, P. Katajisto, M. Enge, H. Rannikmae, M. A. de la Roche, J. Taipale
The paper identifies a shared genomic region upstream of Myc that is critical for both intestinal regeneration and cancer, revealing a genetic link between tissue renewal and tumorigenesis.
bioRxiv · Nov 4, 2022Cancer Biology