Author

M. F. Mojica

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Approach:statistical model· 1 Approach:variational autoencoder· 1

Frequent Co-Authors

R. A. Bonomo· 2 shared S. Haider· 2 shared A. J. Mulholland· 1 shared A. J. Vila· 1 shared A. R. Mack· 1 shared A. S. F. Oliveira· 1 shared C. L. Tooke· 1 shared D. Bhowmik· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiophysics

R. A. Bonomo

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2 papers

Recent·Most cited

BiophysicsbioRxivOct 25, 2022

Gating interactions steer loop conformational changes in the active site of the L1 metallo-β-lactamase

Z. Zhao, X. Shen, S. Chen…·S. Haider

The paper investigates how gating interactions between loops in the L1 metallo-β-lactamase affect active site conformational changes and identifies key residues critical for enzyme activity.

DOI 10.7554/elife.83928

structural biologydeep learning

𝕏 PostBluesky

BiophysicsbioRxivDec 30, 2020

Allosteric communication in Class A β-lactamases occurs via Cooperative Coupling of Loop Dynamics

I. Galdadas, S. Qu, A. S. F. Oliveira…·S. Haider

This study identifies allosteric communication pathways in Class A β-lactamases using molecular dynamics simulations, showing how amino acid substitutions affect enzyme activity and antibiotic resistance.

DOI 10.7554/elife.66567

structural biologydeep learning

𝕏 PostBluesky