Author

M. Goepp

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

C. Yao· 2 shared S. Narumiya· 2 shared Y. Zhou· 2 shared A. G. Rossi· 1 shared A. Rossi· 1 shared B. Zhang· 1 shared C. Robb· 1 shared D. Smyth· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

C. Yao

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Metabolic regulation by prostaglandin E2 impairs lung group 2 innate lymphoid cell responses

C. Robb, Y. Zhou, J. Felton, B. Zhang, M. Goepp, P. Jheeta, D. Smyth, R. Breyer, S. Narumiya, H. McSorley, R. Maizels, J. Schwarze, A. Rossi, C. Yao

This study identifies that PGE2-EP2 signaling suppresses lung ILC2 responses and eosinophilic inflammation, while EP4 agonism restricts these responses, offering potential therapeutic targets for asthma and NERD.

bioRxiv · Dec 23, 2021Immunology

Prostaglandin E2 directly inhibits the conversion of inducible regulatory T cells through EP2 and EP4 receptors via antagonizing TGF-β signalling

M. Goepp, S. Crittenden, Y. Zhou, A. G. Rossi, S. Narumiya, C. Yao

This study shows PGE2 inhibits inducible Treg cell differentiation via EP2 and EP4 receptors by blocking TGF-β signaling in vitro and in vivo.

bioRxiv · Apr 19, 2021Immunology