M. Grange

Antiviral activity of intracellular nanobodies targeting the influenza virus RNA-polymerase core

This paper identifies an intracellular nanobody that inhibits influenza A virus RNA-polymerase by blocking PA-PB1 dimer nuclear import, showing potential for antiviral development.

NECing goes: flexibility of the herpesvirus nuclear egress complex

This study examines the structure and flexibility of the herpesvirus nuclear egress complex (NEC) using electron cryo-tomography, revealing its hexameric lattice and role in capsid envelopment.

In situ structures from relaxed cardiac myofibrils reveal the organization of the muscle thick filament

This study reveals the 3D structure of relaxed cardiac sarcomeres using cryo-electron tomography, showing how thick filament components interact and function in muscle contraction.

Cryo-plasma FIB/SEM volume imaging of biological specimens

This paper introduces cryo-plasma FIB/SEM for high-resolution 3D imaging of biological samples, achieving resolutions of 20-50 nm and enabling in-situ structural biology applications.

Plasma FIB milling for the determination of structures in situ

This paper demonstrates plasma-coupled ion sources for thinning vitrified human cells to enable pseudo-atomic structure determination in situ.

Structure of the thin filament in native skeletal muscles reveals its interaction with nebulin and two distinct conformations of myosin

The paper presents the first structure of native nebulin bound to thin filaments in sarcomeres, revealing interactions with actin and myosin conformations, and the molecular basis of nebulin's role in muscle function.

Demographics and Employment of Max-Planck Society's Postdocs

The paper surveys Max Planck Society postdocs to assess demographics, employment conditions, and disparities in access to employment types, wages, and social benefits.

Molecular plasticity of the native mouse skeletal sarcomere revealed by cryo-ET

This study uses cryo-ET to reveal the molecular architecture of mouse skeletal sarcomeres, showing detailed interactions and conformational plasticity in actin and myosin filaments.