Author

M. Hashemi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 7 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:chromatin & epigenetic regulation· 3 Approach:statistical model· 3 Assay:ATAC-seq· 1 Approach:Bayesian inference· 1 Research Focus:drug response / drug discovery· 1 Assay:Hi-C· 1 Organism:human· 1

Frequent Co-Authors

Y. L. Lyubchenko· 7 shared A. Kolomeisky· 2 shared S. Banerjee· 2 shared S. Vemulapalli· 2 shared Y. Wang· 2 shared Z. Sun· 2 shared K. K. Bhakat· 1 shared K. Zagorski· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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7 shared papersBiophysics

Y. L. Lyubchenko

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Nanoscale interaction of endonuclease APE-1 with DNA characterized by atomic force microscopy

S. Vemulapalli, M. Hashemi, Y. Chen, S. Pramanik, K. K. Bhakat, Y. L. Lyubchenko

This study uses atomic force microscopy to visualize APE1-DNA interactions, revealing APE1's affinity for G-rich DNA and its ability to form loops between DNA segments.

bioRxiv · Feb 11, 2024 · PreprintBiophysics

Assembly of Synaptic Protein-DNA Complexes: Critical Role of Non-Specific Interactions

S. Vemulapalli, M. Hashemi, A. Kolomeisky, Y. L. Lyubchenko

The paper investigates the stability of SfiI-DNA complexes using single-molecule fluorescence and develops a theoretical model to explain the role of non-specific DNA interactions in synaptic protein-DNA complex assembly.

bioRxiv · Apr 27, 2023 · PreprintBiophysics

Bayesian Pharmacometrics Analysis of Baclofen for Alcohol Use Disorder

N. Baldy, M. Hashemi, N. Simon, V. Jirsa

This study uses Bayesian pharmacometrics to estimate Baclofen PK parameters in AUD patients, showing accurate predictions using HMC algorithms with informative priors.

bioRxiv · Oct 25, 2022 · PreprintPharmacology & Toxicology

Sequence Dependent Internucleosomal Interactions Dominate Array Assembly

Y. Wang, T. D. Stormberg, M. Hashemi, A. Kolomeisky, Y. L. Lyubchenko

This study investigates how DNA sequence and internucleosomal interactions influence nucleosome array compaction using Atomic Force Microscopy and develops a theoretical model to explain the results.

bioRxiv · Jul 20, 2022 · PreprintBiophysics

Restriction of RecG translocation by DNA mispairing

Z. Sun, Y. Wang, M. Hashemi, P. Bianco, Y. L. Lyubchenko

This study investigates how DNA mispairing affects RecG helicase translocation using AFM, finding that certain mismatches block movement while others do not.

bioRxiv · Mar 31, 2021Biophysics

Cholesterol in membranes facilitates aggregation of amyloid beta protein at physiologically low concentrations

S. Banerjee, M. Hashemi, K. Zagorski, Y. L. Lyubchenko

This study shows cholesterol in membranes enhances Aβ42 aggregation at low concentrations through AFM imaging and computational modeling.

bioRxiv · Sep 6, 2020Biophysics

Spontaneous Self-assembly of Amyloid β (1-40) into Dimers

M. Hashemi, Y. Zhang, Z. Lv, Y. L. Lyubchenko

This study uses molecular dynamics simulations to show that Aβ(1-40) monomers form stable dimers through specific inter-peptide interactions, without forming long β-strands typical of fibrils.

bioRxiv · Jun 4, 2019Biophysics

Nanoscale Dynamics of Centromere Nucleosomes and the Critical Roles of CENP-A

M. P. Stumme-Diers, S. Banerjee, M. Hashemi, Z. Sun, Y. L. Lyubchenko

This study uses high-speed atomic force microscopy to observe CENP-A nucleosome dynamics, revealing spontaneous conformational changes and unique stabilization properties compared to H3 cores.

bioRxiv · May 3, 2017Biophysics