Modeling High-grade serous ovarian carcinoma using a combination of in vivo electroporation and CRISPR/Cas9 mediated genome editing
K. Teng, M. J. Ford, K. Harwalkar…·Y. Yamanaka
This paper develops a method to generate HGSC mouse models using in vivo electroporation and CRISPR/Cas9, showing that specific gene mutations lead to different tumor characteristics.