M. M. Islam

The paper develops NLM-CKN, a semantic knowledge network linking cell phenotypes to diseases and drugs using integrated data from 88 datasets.

This paper introduces a model for k-mer frequency change based on a birth-death-migration process to estimate maximum likelihood phylogenies without sequence alignment.

The paper describes the engineering, production, and characterization of the Mtb EfpA drug exporter, including its reconstitution in lipid nanoparticles and structural insights.

The paper shows HIV-1 Vpu forms stable aqueous oligomers via its transmembrane domain self-association, identified through cryoEM, EPR, and size exclusion chromatography.

The paper presents functional scores for 2172 BRCA1 variants using a multiplexed HDR assay, showing 93% sensitivity and 100% specificity in classifying pathogenic and benign variants.

This study investigates the oligomeric structures of HIV-1 Vpu protein in solution and lipid environments, revealing novel forms and environmental effects on oligomer stability.

The paper develops a high-content imaging platform to quantify lipid trafficking in leukocytes, showing lipid mobilization correlates with LDL uptake and helps distinguish hypercholesterolemia cases.

The paper reports higher CD8 and CD4 gene expression in the uterus of pregnant ewes compared to non-pregnant ewes, suggesting their potential as markers for pregnancy detection in sheep.

This study evaluates the effects of honeyweed and buckwheat supplemented diets on broiler chicks, finding that a specific combination improves growth, feed efficiency, and blood lipid profiles.

The paper identifies a chimeric ED3 mutant that generates antisera serospecific to both DENV3 and DENV4, revealing that epitope grafting alone is insufficient for serospecificity transfer.

This study develops a collagen-based scaffold with a sustained release of anti-VEGF drug for corneal transplantation and validates its properties in vitro.

This study shows that nanometer-scale protein aggregates can increase immunogenicity in vivo, using BPTI-19A as a model.

This paper develops a nano toolbox for corneal implants that enables drug release, infection response, regeneration promotion, and in situ monitoring of the corneal environment.