Author

M. P. Griffith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 8

Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 5 Approach:experimental assay· 4 Approach:statistical model· 4 Organism:bacteria (other)· 3 Research Focus:clustering· 3 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2

Frequent Co-Authors

D. Van Tyne· 7 shared D. R. Evans· 4 shared L. H. Harrison· 4 shared V. S. Cooper· 4 shared Y. Doi· 4 shared M. M. Mustapha· 3 shared C. L. McElheny· 2 shared H. R. Nordstrom· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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7 shared papersMicrobiology

D. Van Tyne

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8 papers

Recent·Most cited

Harnessing the diversity of Burkholderia spp. prophages for therapeutic potential

H. R. Nordstrom, M. P. Griffith, V. R. Srinivasa, N. R. Wallace, A. Li, V. S. Cooper, R. K. Shields, D. Van Tyne

The paper identifies prophages in Burkholderia spp. genomes that show lytic activity against conspecific and heterospecific isolates, suggesting their potential for phage therapy.

bioRxiv · Jan 24, 2024 · PreprintMicrobiology

Evolution of extended-spectrum β-lactamase-producing ST131 Escherichia coli at a single hospital over 15 years

S.-T. Cho, E. G. Mills, M. P. Griffith, H. R. Nordstrom, C. L. McElheny, L. H. Harrison, Y. Doi, D. Van Tyne

This study tracks the evolution of ST131 E. coli over 15 years at a single hospital, identifying dominant subclades and genetic adaptations associated with ESBL production.

bioRxiv · Dec 11, 2023 · PreprintMicrobiology

In vivo evolution of a Klebsiella pneumoniae capsule defect promotes complement-mediated opsono-phagocytosis and persistence during recurrent infection

W. Bain, B. Ahn, H. Penaloza, C. McElheny, N. Tolman, R. van der Geest, S. Gonzalez-Ferrer, N. Chen, X. An, R. Hosuru, M. Tabary, E. Papke, N. Kohli, N. Farooq, W. Bachman, , J. Lee

The paper identifies a capsule defect in K. pneumoniae that enhances complement-mediated opsonophagocytosis and persistence during recurrent infections.

bioRxiv · May 31, 2023 · PreprintMicrobiology

Genomic diversity of hospital-acquired infections revealed through prospective whole genome sequencing-based surveillance

M. M. Mustapha, V. R. Srinivasa, M. P. Griffith, S.-T. Cho, D. R. Evans, K. Waggle, C. Ezeonwuka, D. Snyder, J. W. Marsh, L. H. Harrison, V. S. Cooper, D. Van Tyne

This study uses whole-genome sequencing to analyze 3,004 bacterial isolates from hospitalized patients, revealing genomic diversity and evolutionary rates across 97 species and informing outbreak detection.

bioRxiv · Oct 27, 2021Microbiology

Carbapenem-Resistant Acinetobacter baumannii in US hospitals: diversification of circulating lineages and antimicrobial resistance

A. V. Iovleva, M. M. Mustapha, M. P. Griffith, L. Komarow, C. Luterbach, D. R. Evans, E. Cober, S. S. Richter, K. Rydell, C. A. Arias, J. T. Jacob, R. A. Salata, M. J. Satlin, D. Wong, R. A. Bonomo, , Y. Doi

This study analyzes CRAb isolates from US hospitals using WGS, identifying new sub-lineages and resistance patterns, highlighting shifts in CRAb population structure and clinical impact.

bioRxiv · Sep 21, 2021 · PreprintMicrobiology

Clinical and genomic epidemiology of carbapenem-non-susceptible Citrobacter spp. at a tertiary healthcare center over two decades

A. Babiker, D. R. Evans, M. P. Griffith, C. L. McElheny, M. Hassan, L. G. Clarke, R. T. Mettus, L. H. Harrison, Y. Doi, R. K. Shields, D. Van Tyne

The paper analyzes the clinical and genomic epidemiology of carbapenem-non-susceptible Citrobacter spp. over two decades, finding increased prevalence and genetic diversity with carbapenemase-encoding plasmids.

Journal of Clinical Microbiology · Aug 24, 2020Peer-reviewedMicrobiology

Comprehensive analysis of horizontal gene transfer among multidrug-resistant bacterial pathogens in a single hospital

D. R. Evans, M. P. Griffith, M. M. Mustapha, J. W. Marsh, A. J. Sundermann, V. S. Cooper, L. H. Harrison, D. Van Tyne

This study tracks horizontal gene transfer of mobile genetic elements in a hospital setting using genomic analysis of 2,173 bacterial isolates.

eLife · Apr 14, 2020Peer-reviewedMicrobiology

Unlocking a high bacterial diversity in the coralloid root microbiome from the cycad genus Dioon

P. d. J. Suarez-Moo, A. Vovides, M. P. Griffith, F. Barona-Gomez, A. Cibrian-Jaramillo

This study characterizes the bacterial diversity in coralloid roots of seven Dioon species and their surrounding environments, revealing shared and distinct microbial communities.

bioRxiv · Aug 2, 2018Microbiology