ImmunologybioRxiv
Single-dose intranasal vaccination elicits systemic and mucosal immunity against SARS-CoV-2
X. An, M. P. Martinez, A. Rezvan…·N. Varadarajan
This study develops an intranasal vaccine that induces systemic and mucosal immunity against SARS-CoV-2 in mice, with single-cell RNA-sequencing confirming T and B cell responses in nasal-associated lymphoid tissues.
DOI 10.1016/j.isci.2021.103037