Pharmacology & ToxicologybioRxiv
Zoledronate extends healthspan and survival via the mevalonate pathway in a FOXO-dependent manner
Z. Chen, J. Cordero, C. Slack…·I. Bellantuono
This study shows zoledronate extends lifespan and healthspan in Drosophila by modulating the mevalonate pathway through FOXO-dependent mechanisms.
DOI 10.1093/gerona/glab172