Author

M. Pardons

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

L. Vandekerckhove· 2 shared N. Chomont· 2 shared P. Gantner· 2 shared A. Pagliuzza· 1 shared B. Autran· 1 shared B. Cole· 1 shared C. Dufour· 1 shared C. Hamimi· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

L. Vandekerckhove

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A truncated HIV Tat demonstrates potent and specific latency reversal activity

E. Van Gulck, M. Pardons, E. Nijs, N. Verheyen, K. Dockx, C. Van Den Eynde, E. Battivelli, J. Vega, E. Florence, B. Autran, N. Archin, D. M. Margolis, C. Katlama, C. Hamimi, I. Van Den Wyngaert, , D. Boden

The paper demonstrates that a truncated HIV Tat protein and mRNA can reactivate HIV-1 in latently infected T-cells as effectively as Phorbol 12-Myristate 13-Acetate without T-cell activation or significant transcriptome changes.

bioRxiv · Mar 2, 2023 · PreprintCell Biology

HIV rapidly targets a diverse pool of CD4+ T cells to establish productive and latent infections

P. Gantner, S. Buranapraditkun, A. Pagliuzza, C. Dufour, M. Pardons, J. L. Mitchell, E. Kroon, C. Sacdalan, N. Tulmethakaan, S. Pinyakorn, M. L. Robb, N. Phanuphak, J. Ananworanich, D. Hsu, S. Vasan, , N. Chomont

This study identifies that HIV initially infects diverse CD4+ T cells in blood and lymph nodes, establishing both productive infections and latent reservoirs simultaneously.

bioRxiv · May 10, 2022Microbiology

In-depth single-cell analysis of translation-competent HIV-1 reservoirs identifies cellular sources of plasma viremia

B. Cole, L. Lambrechts, P. Gantner, Y. Noppe, N. Bonine, W. Witkowski, L. H. Chen, S. Palmer, J. I. Mullins, N. Chomont, M. Pardons, L. Vandekerckhove

This study uses STIP-Seq to analyze HIV-1 reservoirs and identifies proviral features and cellular sources contributing to plasma viremia in ART-suppressed individuals.

bioRxiv · Feb 15, 2021Microbiology