J. R. Friedman

The paper identifies Mmc1, a DRP-like pseudoenzyme that interacts with MICOS to maintain cristae architecture in S. pombe.

This study identifies Mdi1, an intermembrane space protein in yeast essential for mitochondrial fission, showing that Dnm1/Drp1 requires Mdi1 to complete mitochondrial division.

This paper demonstrates isotropic resolution doubling in light-sheet microscopy using oblique plane structured illumination, achieving sub-150nm lateral resolution with reduced phototoxicity and faster volumetric imaging.

This study identifies TMEM11 as a negative regulator of BNIP3/BNIP3L-dependent mitophagy, showing its role in mitochondrial morphology and autophagy regulation.

The paper identifies ER-localized phosphatidylethanolamine synthase (Psd1) as a novel regulator of lipid droplet formation, showing its conserved role across species.

The paper examines how intestinal inflammation affects ACE2 and TMPRSS2 expression and identifies shared molecular networks between COVID-19 and IBD.

This study shows that ITK knockdown increases Foxp3+ TREG differentiation and suppressive function in human T cells, suggesting ITK as a target to enhance TREGs in autoimmune diseases.