Cross-talk between cAMP and Ca2+ signalling in cardiac pacemaker cells involves IP3-evoked Ca2+ release and stimulation of adenylyl cyclase 1
S. J. Bose, M. Read, R. A. Capel, E. Akerman, T. Ayagama, A. Russell, D. A. Terrar, M. Zaccolo, R. A. B. Burton
This study investigates the role of AC1 in atrial pacemaker activity response to β-adrenergic stimulation and IP3R calcium release in mouse and guinea pig atrial tissues.
bioRxiv · Jan 6, 2022 · PreprintPharmacology & Toxicology