Extensive re-modelling of the cell wall during the development of Staphylococcus aureus bacteraemia
E. J. A. Douglas, N. Palk, T. Brignoli, D. Altwiley, M. Boura, M. Laabei, M. Recker, G. C. Cheung, R. Liu, R. C. Hseih, M. Otto, E. O'Brien, R. M. McLoughlin, R. C. Massey
This study identifies TcaA as a key regulator of cell wall remodeling in Staphylococcus aureus during bacteraemia, enhancing virulence by altering wall teichoic acids and peptidoglycan crosslinking.
bioRxiv · Feb 23, 2023 · PreprintMicrobiology