ImmunologybioRxiv
TLR4 signaling and macrophage inflammatory responses are dampened by GIV/Girdin
L. A. B. Swanson, G. D. Katkar, J. Tam…·P. Ghosh
This study shows GIV/Girdin dampens TLR4-mediated inflammatory responses in macrophages by inhibiting receptor dimerization and downstream signaling.
DOI 10.1073/pnas.2011667117