R. Pranadinata

This paper creates a biobank of patient-derived organoids to identify molecular subtypes of Crohn's disease and test subtype-specific therapies.

The paper investigates how WxxxE bacterial effectors interact with ELMO1 to regulate inflammation, showing that ELMO1 differentiates pathogenic from commensal bacteria and enhances inflammatory responses through these interactions.

This study shows GIV/Girdin dampens TLR4-mediated inflammatory responses in macrophages by inhibiting receptor dimerization and downstream signaling.

This study shows that chronic e-cigarette use damages the gut barrier and causes inflammation, driven by non-nicotine chemicals in e-liquids.