Author

M. Sciacovelli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. Frezza· 2 shared C. Schmidt· 2 shared M. Yang· 2 shared A. Dugourd· 1 shared A. Erez· 1 shared A. Mora· 1 shared A. S. Costa· 1 shared A. Von Kriegsheim· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

C. Frezza

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Author profile →

2 papers

Recent·Most cited

FOXA2 controls the anti-oxidant response in FH-deficient cells

C. Rogerson, M. Sciacovelli, L. A. Maddalena, L. Valcarcel-Jimenez, C. Schmidt, M. Yang, E. Ivanova, J. Kent, A. Mora, D. Cheeseman, J. S. Carroll, G. Kelsey, C. Frezza

This study identifies FOXA2 as a key transcription factor regulating the anti-oxidant response in FH-deficient cells, independent of NRF2, and highlights its role in metabolic rewiring.

bioRxiv · Jul 4, 2022Cancer Biology

Nitrogen partitioning between branched-chain amino acids and urea cycle enzymes sustains renal cancer progression

M. Sciacovelli, A. Dugourd, L. Valcarcel Jimenez, M. Yang, E. Nikitopoulou, A. S. Costa, L. Tronci, V. Caraffini, P. Rodrigues, C. Schmidt, D. G. Ryan, T. Young, V. Zecchini, S. H. Rossi, C. Massie, , C. Frezza

This study identifies metabolic reprogramming in renal cancer cells, showing how branched-chain amino acid catabolism and urea cycle enzymes support tumor progression and metastasis.

bioRxiv · Sep 17, 2021 · PreprintCancer Biology