M. Stadler

RNF43 is a gatekeeper for colitis-associated cancer

This study identifies RNF43 mutations as a driver of colitis-associated cancer by showing their role in promoting inflammation and dysbiosis in mouse models and human patients.

The Novel Silver-Containing Antimicrobial Potentiates Aminoglycoside Activity Against Pseudomonas aeruginosa.

This study shows that AGXX(R), a silver-containing antimicrobial, enhances aminoglycoside activity against Pseudomonas aeruginosa by increasing ROS production, membrane permeability, and reducing resistance.

Building a genome-based understanding of bacterial pH preferences

The paper compiles bacterial distribution data and genomic information to develop a machine learning model predicting bacterial pH preferences from genomic data.

Neurotrophic and immunomodulatory lanostane triterpenoids from wood-inhabiting Basidiomycota

This study identifies lanostane triterpenoids from medicinal mushrooms that enhance neurotrophic factors ngf and bdnf without cytotoxicity, suggesting potential for neurodegenerative disease treatment.

Single-cell analysis reveals inter- and intratumour heterogeneity in metastatic breast cancer

This study uses single-cell RNA-Seq to identify molecular states and partial EMT phenotypes in breast cancer tumours and metastases, revealing common transcription factors across patients.