Author

M. T. Harper

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Organism:Drosophila· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

G. Ladds· 2 shared A. Chandran· 1 shared A. Inoue· 1 shared B. Al-Zaid· 1 shared D. I. Mackie· 1 shared D. R. Poyner· 1 shared D. Safitri· 1 shared D. Wootten· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersPharmacology & Toxicology

G. Ladds

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintApr 8, 2021

RAMPs regulate signalling bias and internalisation of the GIPR

M. Harris, D. I. Mackie, J. B. Pawlak…·G. Ladds

This study shows RAMPs modulate GIPR signaling and internalization, with RAMP3 reducing cAMP production and promoting surface retention, while RAMP1/2 decrease Gq/11/15 activation, and RAMP1 is essential for normal glucose regulation.

DOI 10.1101/2021.04.08.436756

mouseexperimental assay

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BiochemistrybioRxivJan 3, 2020

Proposed model of the Dictyostelium cAMP receptors bound to cAMP

J. C. Greenhalgh, A. Chandran, M. T. Harper…·T. Rahman

The paper presents homology models of cAMP receptors from Dictyostelium discoideum, highlighting structural features that may explain differential cAMP binding affinities and activation mechanisms.

DOI 10.1016/j.jmgm.2020.107662

Drosophiladeep learning

𝕏 PostBluesky