Author

M. Vinci

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Organism:human· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Approach:Bayesian inference· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Sottoriva· 2 shared C. Jones· 2 shared H. Tari· 2 shared K. Kessler· 2 shared A. Burford· 1 shared A. Comba· 1 shared A. J. Nicola Candia· 1 shared A. M. Sonabend· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

A. Sottoriva

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

H3.3-G34R Mutation-Mediated Epigenetic Reprogramming Leads to Enhanced Efficacy of Immune Stimulatory Gene Therapy in Diffuse Hemispheric Gliomas

M. B. Garcia Fabiani, S. Haase, K. Banerjee, Z. Zhu, B. McClellan, A. Mujeeb, Y. Li, C. E. Tronrud, M. L. Varela, M. E. J. West, J. Yu, P. Kadiyala, A. Taher, F. J. NUNEZ, M. S. Alghamri, , Sart

This study shows that H3.3-G34R mutations reprogram the tumor immune microenvironment in diffuse hemispheric gliomas, enhancing the efficacy of immune stimulatory gene therapy and leading to long-term survival in treated mice.

bioRxiv · Jun 13, 2023 · PreprintCancer Biology

Quantification of spatial subclonal interactions enhancing the invasive phenotype of paediatric glioma

H. Tari, K. Kessler, N. Trahearn, B. Werner, M. Vinci, C. Jones, A. Sottoriva

This study quantifies spatial subclonal interactions in paediatric gliomas that enhance invasive phenotype, distinguishing true interactions from spatial confounding factors.

bioRxiv · Jul 19, 2021 · PreprintCancer Biology

Loss of the H4 lysine methyltransferase KMT5B drives tumorigenic phenotypes by depleting H3K27me3 at loci otherwise retained in H3K27M mutant DIPG cells

K. Kessler, A. Mackay, Y. Grabovska, V. Molinari, A. Burford, S. Temelso, H. Tari, E. Yara-Romero, I. Liu, L. Yu, D. Castel, J. Choudhary, A. Sottoriva, M. Filbin, M. Vinci, C. Jones

The paper shows that loss of KMT5B in DIPG cells depletes retained H3K27me3 loci, leading to transcriptional changes that promote tumorigenesis.

bioRxiv · Jul 19, 2021 · PreprintCancer Biology

SCA-1 micro-heterogeneity in the fate decision of dystrophic fibro/adipogenic progenitors

G. Giuliani, S. Vumbaca, C. Fuoco, C. Gargioli, E. Giorda, G. Massacci, A. Palma, A. Reggio, F. Riccio, M. Vinci, L. Castagnoli, G. Cesareni

The paper investigates micro-heterogeneity in dystrophic fibro/adipogenic progenitors (FAPs) using SCA-1 expression levels and shows differential adipogenic and fibrogenic responses between two FAP states.

bioRxiv · May 14, 2020Cell Biology