Author

M. Filbin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 5 Assay:bulk RNA-seq· 4 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2

Frequent Co-Authors

L. Jiang· 2 shared S. Venneti· 2 shared A. Bhaduri· 1 shared A. Burford· 1 shared A. Chinnaiyan· 1 shared A. G. Therien· 1 shared A. M. Chinnaiyan· 1 shared A. Mackay· 1 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCancer Biology

L. Jiang

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Common molecular features of H3K27M DMGs and PFA ependymomas map to hindbrain developmental pathways

M. Pun, D. Pratt, P. R. Nano, P. K. Joshi, L. Jiang, B. Englinger, A. Rao, M. Cieslik, A. M. Chinnaiyan, K. Aldape, S. Pfister, M. Filbin, A. Bhaduri, S. Venneti

The paper identifies shared molecular features between H3K27M diffuse midline gliomas and PFA ependymomas, linking them to hindbrain developmental pathways.

bioRxiv · Nov 17, 2022Cancer Biology

Novel neutrophil subsets associated with sepsis, vascular dysfunction and metabolic alterations identified using systems immunology

R. Martinelli, U. Parthasarathy, Y. Kuang, G. Thakur, J. D. Hogan, T. P. Wyche, J. E. Norton, J. R. Killough, T. R. Sana, C. Beakes, B. Shyong, R. N. Zhang, D. A. Gutierrez, M. Filbin, D. C. Christiani, , C. H. White

The paper identifies novel neutrophil subsets in sepsis patients using systems immunology and links them to cytokines, metabolites, and lipids, enabling a predictive model for patient classification.

bioRxiv · Feb 1, 2022 · PreprintImmunology

Loss of the H4 lysine methyltransferase KMT5B drives tumorigenic phenotypes by depleting H3K27me3 at loci otherwise retained in H3K27M mutant DIPG cells

K. Kessler, A. Mackay, Y. Grabovska, V. Molinari, A. Burford, S. Temelso, H. Tari, E. Yara-Romero, I. Liu, L. Yu, D. Castel, J. Choudhary, A. Sottoriva, M. Filbin, M. Vinci, C. Jones

The paper shows that loss of KMT5B in DIPG cells depletes retained H3K27me3 loci, leading to transcriptional changes that promote tumorigenesis.

bioRxiv · Jul 19, 2021 · PreprintCancer Biology

Early cross-coronavirus reactive signatures of protective humoral immunity against COVID-19

P. Kaplonek, C. Wang, Y. Bartsch, S. Fischinger, M. J. Gorman, K. Bowman, J. Kang, D. Dayal, P. Martin, R. Nowak, C.-L. Hsieh, J. Feldman, B. Juelg, E. Nilles, E. R. Musk, , G. Alter

The paper profiles early humoral immune responses in COVID-19 patients, finding that survivors show rapid SARS-CoV-2-specific immunity linked to pre-existing OC43 immunity, while non-survivors have delayed and blunted responses.

bioRxiv · May 11, 2021 · PreprintImmunology

Therapeutic reversal of prenatal pontine ID1 signaling in DIPG

V. N. Yadav, M. K. Harris, D. Messinger, C. Thomas, J. R. Cummings, T. Yang, R. Woo, R. Siddaway, M. Burkert, S. Stallard, T. Qin, B. Mullan, R. Siada, R. Ravindran, M. Niculcea, , C. Koschmann

This study identifies ID1 upregulation in DIPG tumor cells and shows that CBD can reduce ID1-driven invasiveness in vitro and in vivo.

bioRxiv · May 10, 2021 · PreprintCancer Biology