M. Zimmer

AlphaFold2 and RoseTTAFold Predict Posttranslational modifications. Chromophore Formation in GFP-like Proteins.

This study shows AlphaFold2 and RoseTTAFold can predict whether GFP-like proteins will form a chromophore based on sequence alone, using structural and chemical insights.

Modular deep learning enables automated identification of monoclonal cell lines

This paper introduces Monoqlo, a deep learning workflow that automatically detects colony presence and identifies clonality from cellular imaging, enabling scalable and standardized monoclonalization.

A direct RNA-protein interaction atlas of the SARS-CoV-2 RNA in infected human cells

This study maps direct RNA-protein interactions of SARS-CoV-2 RNA in infected human cells using RAP-MS, identifying host factors, regulators, and potential drug targets involved in viral replication and host defense.

Jasmonate biosynthesis arising from altered cell walls is prompted by turgor-driven mechanical compression and guides root hydrotropism

The paper shows that mechanical compression from enlarged cortex cells increases JA-Ile biosynthesis, which directs root hydrotropism.

WHIMP links the actin nucleation machinery to Src-family kinase signaling during protrusion and motility

This paper identifies WHIMP as a new WASP-family protein that enhances cell motility through actin assembly and activates Src-family kinases, modulating WASP-family protein activation during protrusion.

Inhibition of jasmonate-mediated plant defences by the fungal metabolite higginsianin B

This study identifies higginsianin B, a fungal metabolite that inhibits plant jasmonate signaling by blocking JAZ protein degradation.

Shoot-to-root translocation of the jasmonate precursor 12-oxo-phytodienoic acid (OPDA) coordinates plant growth responses following tissue damage

This study identifies OPDA as a mobile jasmonate precursor that translocates from damaged shoots to roots, coordinating growth responses in Arabidopsis.