Meng‐Chieh Shen

This study shows that a high-cholesterol diet in zebrafish leads to hypercholesterolemia and fasting-induced liver triglyceride accumulation, with lipid accumulation in adipocytes contributing to hepatic steatosis.

WheresWalker is a mutation mapping pipeline that rapidly identifies mutation-containing intervals in whole genome sequencing data, validated in zebrafish and maize.

This study shows that Hedgehog signaling regulates neurogenesis in the larval and adult zebrafish hypothalamus by promoting proliferation of neural precursors and maintaining a heterogeneous signaling environment.

The paper analyzes mRNA processing in zebrafish mutant lines to explain why few phenotypes are observed despite predicted gene disruptions.