Darby W. Kozan

This study shows that loss of asgr1a in zebrafish leads to excess dietary cholesterol excretion rather than hepatic accumulation, suggesting a role for ASGR1 in cholesterol metabolism.

This study shows that a high-cholesterol diet in zebrafish leads to hypercholesterolemia and fasting-induced liver triglyceride accumulation, with lipid accumulation in adipocytes contributing to hepatic steatosis.

The paper compares transposon mutagenesis methods in yeast to infer gene essentiality, finding biases in insertion sites and recommending transposon choices for accurate essentiality prediction.