BiochemistrybioRxiv
mTOR-driven widespread exon skipping renders multifaceted gene regulation and proteome complexity
S. Cheng, N. A. Fahmi, M. Park…·J. Yong
This study shows that mTOR hyperactivation causes widespread exon skipping, leading to diverse proteomic changes through alternative splicing in both 5’-UTR and coding regions.
DOI 10.3390/ijms232012416