BiochemistrybioRxiv
Biosynthesis of Isonitrile Lipopeptides by Conserved Non-ribosomal Peptide Synthetase Gene Clusters in Actinobacteria
N. C. Harris, M. Sato, N. A. Herman…·W. Zhang
The paper identifies a conserved gene cluster in Actinobacteria that synthesizes isonitrile lipopeptides (INLPs) via a unique thio-template mechanism and links it to metal transport in Mycobacterium marinum.