Cancer BiologybioRxiv
Simultaneous Targeting of XPO1 and BCL2 as an Effective Treatment Strategy for Double-Hit Lymphoma
Y. Liu, N. Azizian, Y. Dou…·Y. Li
This study shows that combining XPO1 and BCL2 inhibitors effectively treats double-hit lymphoma by suppressing MYC and BCL2 oncogenes, reducing tumor growth and preventing metastasis.
DOI 10.1186/s13045-019-0803-9