N. Babel

Stable Equilibria under Random Fitness and Recombination Rates

The paper analyzes a two-locus genetic model with random recombination rates and fitness matrices, showing genotype clustering and attraction regions dependent on recombination and fitness parameters.

Increased migratory/activated CD8+ T cell and low avidity SARS-CoV-2 reactive cellular response in post-acute COVID-19 syndrome

This study identifies increased migratory CD8+ T cells and low avidity SARS-CoV-2 reactive responses in post-acute COVID-19 syndrome patients compared to healthy convalescents.

Impaired cytotoxic CD8+ T cell response in elderly COVID-19 patients

This study examines CD8+ T cell cytotoxicity in mild COVID-19 patients, finding reduced cytotoxic potential in elderly individuals over 80 years old.

SARS-CoV-2 reactive T cells in uninfected individuals are likely expanded by beta-coronaviruses

The paper identifies beta-coronaviruses as the likely source of pre-existing SARS-CoV-2 reactive T cells in uninfected individuals by analyzing epitope predictions and pathogen similarity.

Sex-associated differences in cytomegalovirus prevention: Prophylactic strategy is associated with a strong kidney function impairment in female renal transplant patients

This study compares prophylactic and pre-emptive strategies for preventing CMV syndrome in renal transplant patients, finding that the prophylactic strategy impairs kidney function in females.

BKV clearance time correlates with exhaustion state and T-cell receptor repertoire shape of BKV-specific T-cells in renal transplant patients

The paper investigates factors affecting BKV clearance in kidney transplant patients, finding that T-cell receptor diversity and exhaustion status, not clone numbers, correlate with clearance duration.

A novel approach reveals that HLA class 1 single antigen bead-signatures provide a means of high-accuracy pre-transplant risk assessment of acute cellular rejection

This paper develops a novel method using HLA class 1 single antigen bead signatures to predict acute cellular rejection risk pre-transplant with high accuracy.