Author

N. C. Hoang

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Biochemistry· 1

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Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

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A. Bellina· 1 shared C.-X. Wu· 1 shared J. Liao· 1 shared L. Wan· 1 shared M. Federici· 1 shared M. Oh· 1 shared M. R. Cookson· 1 shared M. Wang· 1 shared

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2019-2019 · peak 1/yr

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1 shared paperBiochemistry

A. Bellina

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintJun 23, 2019

A revised 1.6 Å structure of the GTPase domain of the Parkinson’s disease-associated protein LRRK2 provides insights into mechanisms

C.-X. Wu, J. Liao, Y. Park…·Q. Q. Hoang

This paper reports a 1.6 Å crystal structure of the GTPase domain of LRRK2, revealing how PD-associated mutations at Arg-1441 impair nucleotide-dependent conformational dynamics.

DOI 10.1101/676627

humanprotein structure

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