Author

N. Decher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Assay:electrophysiology· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. K. Kiper· 1 shared B. C. Juers· 1 shared B. Eymsh· 1 shared B. Wuensch· 1 shared E. B. Riel· 1 shared E. Wrobel· 1 shared F.-R. Schmid· 1 shared G. Seebohm· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiophysics

A. K. Kiper

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2 papers

Recent·Most cited

Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K2P channel TALK-2

L. C. Neelsen, E. B. Riel, S. Rinne, F.-R. Schmid, B. C. Juers, M. Bedoya, J. P. Langer, B. Eymsh, A. K. Kiper, S. Cordeiro, N. Decher, T. Baukrowitz, M. Schewe

This paper identifies a lower cytoplasmic gate in TALK-2 channels and demonstrates bidirectional coupling between this gate and the selectivity filter gate, showing that ion occupancy and stimuli can influence both gates.

bioRxiv · Nov 22, 2023Biophysics

An Activator Locks Kv7.1 Channels Open by Electro-Mechanical Uncoupling and Allosterically Modulates its Pore with similarity to phosphatidylinositol-4,5-bisphosphat

M. Moeller, J. A. Schreiber, M. Zaydman, Z. Beller, S. Becker, N. Ritter, E. Wrobel, N. Strutz-Seebohm, N. Decher, J. Cui, N. Schmidt, M. Duefer, B. Wuensch, G. Seebohm

This study identifies two independent mechanisms by which (R)-L3 activates Kv7.1 channels, involving allosteric modulation of the pore and electro-mechanical uncoupling.

bioRxiv · Feb 11, 2021 · PreprintBiophysics