Author

N. Deshpande

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Assay:clinical cohort / trial· 1 Assay:DNA methylation· 1

Frequent Co-Authors

B. J. Cochran· 2 shared B. Manandhar· 2 shared K.-A. Rye· 2 shared M. Wilkins· 2 shared A. Bianchi· 1 shared A. I. Pund· 1 shared A. Jakati· 1 shared B. Reischl· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

B. J. Cochran

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ApoA-I Protects Pancreatic β-cells from Cholesterol-induced Mitochondrial Damage and Restores their Ability to Secrete Insulin

B. Manandhar, E. Pandzic, N. Deshpande, S.-Y. Chen, V. Wasinger, M. Kockx, E. N. Glaros, K. L. Ong, S. R. Thomas, M. Wilkins, R. Whan, B. J. Cochran, K.-A. Rye

This study shows apoA-I improves β-cell insulin secretion by reducing oxidative stress and enhancing mitochondrial function in cholesterol-loaded cells.

bioRxiv · Apr 3, 2023Cell Biology

Effect of insulin insufficiency on ultrastructure and function in skeletal muscle

C. Kopecky, M. Haug, B. Reischl, N. Deshpande, B. Manandhar, T. King, V. Lee, M. Wilkins, M. J. Morris, P. Polly, O. Friedrich, K.-A. Rye, B. J. Cochran

This study investigates how insulin deficiency affects skeletal muscle structure and function in mice with beta-cell dysfunction, finding that insulin supplementation restores muscle integrity and gene expression.

bioRxiv · Dec 18, 2022Physiology

Neutrophil-Mediated Stromal-Tumor IL-6/STAT-3 Signaling Underlies the Association between Neutrophil-to-Lymphocyte Ratio Dynamics and Chemotherapy Response in Localized Pancreatic Cancer: A Hybrid Clinical-Preclinical Study

I. de Castro Silva, P. Sharma, A. Bianchi, N. Deshpande, S. Mehra, J. England, P. J. Hosein, D. Kwon, N. Merchant, J. Datta

This study shows that neutrophil-to-lymphocyte ratio (NLR) dynamics predict chemotherapy response in pancreatic cancer and that targeting NLR improves chemosensitivity by modulating IL-6/STAT-3 signaling.

bioRxiv · May 4, 2022 · PreprintImmunology

Phylogenetic diversity and activity screening of cultivable actinobacteria isolated from marine sponges and associated environments from the western coast of India

U. Baig, N. Dahanukar, N. Shintre, K. Holkar, A. I. Pund, U. Lele, T. Gujarathi, K. Patel, A. Jakati, R. Singh, H. Vidwans, V. Tamhane, N. Deshpande, M. Watve

The paper studies actinobacteria from marine sponges and associated environments, identifying new species and reporting predatory behavior and antibacterial activity.

Access Microbiology · Sep 23, 2021Peer-reviewedMicrobiology