T. King

Analysis of ductal carcinoma in situ by self-reported race reveals molecular differences related to outcome.

The paper analyzes molecular differences in ductal carcinoma in situ (DCIS) by self-reported race and outcome groups, identifying variations in gene expression, tumor microenvironment, and copy number variations between Black and White women.

Effect of insulin insufficiency on ultrastructure and function in skeletal muscle

This study investigates how insulin deficiency affects skeletal muscle structure and function in mice with beta-cell dysfunction, finding that insulin supplementation restores muscle integrity and gene expression.

Shorter constant work rate cycling tests as proxies for longer tests in highly trained cyclists

This study shows that a 2-minute constant work rate cycling test can serve as a proxy for a 4-minute test in highly trained cyclists, as it correlates strongly with longer test outcomes while being less fatiguing.

Large ecological benefits of small urban greening actions

The paper shows that small urban greening actions can lead to significant ecological benefits, including increased insect diversity and community interactions within three years.

DCIS genomic signatures define biology and clinical outcome: Human Tumor Atlas Network (HTAN) analysis of TBCRC 038 and RAHBT cohorts

The paper develops a classifier for DCIS recurrence using genomic data from two cohorts and identifies pathways and stroma-specific signatures associated with progression to invasive cancer.

SARS-CoV-2 Spreads through Cell-to-Cell Transmission

This study shows SARS-CoV-2 spreads through cell-to-cell contact via spike glycoprotein, which is more efficient than SARS-CoV and resistant to neutralizing antibodies.

Age and infectious dose significantly affect disease progression after RHDV2 infection in naive domestic rabbits

This study investigates the virulence of RHDV2 in rabbits, finding 100% case fatality rate regardless of age or dose, with disease symptoms appearing late in infection.

Paternal hypoxia exposure primes offspring for increased hypoxia resistance

This study shows that paternal hypoxia exposure increases offspring hypoxia tolerance through upregulated hemoglobin genes, without detectable methylation changes.

Host-associated fungal communities are determined by host phylogeny and exhibit widespread associations with the bacterial microbiome

The paper shows fungal communities in hosts are shaped by host phylogeny and interact with bacterial microbiomes across 49 species.

TCR and inflammatory signals tune human MAIT cells to exert specific tissue repair and effector functions

This study investigates how TCR and inflammatory signals shape human MAIT cell functions, revealing their roles in tissue repair and effector responses.

Mathematical Modeling Identifies the Role of Adaptive Immunity as a Key Controller of Respiratory Syncytial Virus (RSV) Titer in Cotton Rats

The paper uses mathematical modeling to show that adaptive immunity significantly reduces RSV titer in cotton rats, with key kinetic features observed in both in vitro and in vivo experiments.

Mathematical Modeling Identifies the Role of Adaptive Immunity as a Key Controller of Respiratory Syncytial Virus (RSV) Titer in Cotton Rats

The paper uses mathematical modeling to show that adaptive immunity significantly reduces RSV titer in cotton rats, with key kinetic features observed in both in vitro and in vivo experiments.