Author

N. Imai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Organism:human· 1

Frequent Co-Authors

D. E. Cohen· 2 shared E. A. Ortlund· 2 shared M. C. Tillman· 2 shared S. J. Hagen· 2 shared Y. Li· 2 shared A. Adhiyaman· 1 shared A. P. Kurland· 1 shared A. R. Patel· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

D. E. Cohen

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Immunological landscape of human lymphoid explants during measles virus infection

J. A. Acklin, A. R. Patel, A. P. Kurland, S. Horiuchi, A. S. Moss, E. J. Degrace, S. Ikegame, J. Carmichael, S. Kowdle, P. Thibault, N. Imai, H. Ueno, B. Tweel, J. R. Johnson, B. R. Rosenberg, , J. K. Lim

The paper infects human lymphoid explants with measles virus and uses scRNA-Seq and flow cytometry to identify B cell preference and T cell resistance, along with ISG protein induction.

bioRxiv · Sep 12, 2022Immunology

Allosteric regulation of Thioesterase Superfamily Member 1 by free fatty acids and lysophosphatidylcholine

M. C. Tillman, N. Imai, Y. Li, M. Khadka, C. D. Okafor, P. Juneja, A. Adhiyaman, S. J. Hagen, D. E. Cohen, E. A. Ortlund

This study identifies the StarD domain of Them1 as a lipid sensor that allosterically regulates its activity and localization in response to fatty acids and lysophosphatidylcholine.

bioRxiv · Feb 18, 2020 · PreprintBiochemistry

Thioesterase Superfamily Member 1 Undergoes Stimulus-coupled Reorganization to Regulate Metabolism

Y. Li, N. Imai, S. Goyal, H. T. Nicholls, T. I. Krisko, M. Baqai, L.-H. Ang, M. C. Tillman, E. A. Ortlund, D. E. Cohen, S. J. Hagen

This paper shows that Them1 undergoes conformational changes in response to stimuli, forming biomolecular condensates that regulate fatty acid oxidation and thermogenesis.

bioRxiv · Feb 18, 2020Cell Biology