γδ T cells respond directly and selectively to the skin commensal yeast Malassezia for IL-17-dependent fungal control.
F. Ruchti, M. Tuor, L. Mathew, N. McCarthy, S. LeibundGut-Landmann
This study identifies Vγ4+ γδ T cells as key mediators of IL-17-dependent fungal control against Malassezia in skin, showing memory-like responses and direct recognition of fungal ligands.
bioRxiv · Sep 8, 2023 · PreprintImmunology