N. Q. Zhao

Single-cell multi-omic profiling identifies immune dysregulation in severe COVID-19, including neutrophil hyperactivation and anti-inflammatory monocytes.

The paper responds to criticisms of a previous study on transdifferentiation of plasmablasts to neutrophils in severe COVID-19 using single-cell transcriptomic data.

This study examines how treated HIV infection affects NK cell phenotype and function, finding altered repertoires but no increased HIV-specificity.

This study uses mass cytometry to analyze how daclizumab beta affects NK cell phenotypes in RMS patients, showing distinct changes in CD56bright and CD56dim subsets.

This study shows that TIGIT is upregulated on NK cells in untreated HIV+ individuals and marks a functional, mature NK cell subset with enhanced responses to HIV-infected targets.

This study develops bispecific antibodies targeting HIV gp41 and NK cell CD16 to enhance ADCC against HIV-infected cells, showing improved degranulation and killing of infected targets.