Author

H. W. Ong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. D. Axtman· 2 shared J. L. Smith· 2 shared A. N. Bullock· 1 shared C. I. Wells· 1 shared D. Drewry· 1 shared E. Chang· 1 shared E. R. Lowry· 1 shared H. Wichterle· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPharmacology & Toxicology

A. D. Axtman

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivMay 15, 2023

Optimization of 3-Cyano-7-cyclopropylamino-pyrazolopyrimidines Toward the Development of an In Vivo Chemical Probe for CSNK2

X. Yang, H. W. Ong, R. J. Dickmander…·T. M. Willson

The paper develops analogs of SGC-CK2-1 to improve pharmacokinetic properties in mice by inhibiting GST and P450 enzymes through co-dosing protocols.

DOI 10.1021/acsomega.3c05377

mouseexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivPreprintFeb 9, 2023

A Potent and Selective CDKL5/GSK3 Chemical Probe is Neuroprotective

H. W. Ong, Y. Liang, W. Richardson…·A. D. Axtman

The paper develops a potent and selective CDKL5/GSK3 chemical probe and demonstrates its neuroprotective effects in human motor neurons under ER stress.

DOI 10.1101/2023.02.09.527935

humanexperimental assay

𝕏 PostBluesky