Author

N. Sachs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

L. Maegdefessel· 2 shared Z. Li· 2 shared A. Bartelt· 1 shared A. Busch· 1 shared A. Dueck· 1 shared A. Lyubimova· 1 shared A. Papaspyropoulos· 1 shared A. R. Bausch· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersImmunology

L. Maegdefessel

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Loss of myeloid cannabinoid CB1 receptor confers atheroprotection by reducing macrophage proliferation and immunometabolic reprogramming

Y. Wang, G. Li, B. Chen, G. Shakir, M. Volz, E. van der Vorst, S. Maas, C. Muley, A. Bartelt, Z. Li, N. Sachs, L. Maegdefessel, M. Nazari Jahantigh, M. Hristov, M. Lacy, , S. Steffens

This study shows that loss of myeloid CB1 receptor reduces atherosclerosis in male mice by limiting macrophage proliferation and inflammation, with sex-specific effects observed.

bioRxiv · Apr 6, 2023 · PreprintImmunology

Utilization of an Artery-on-a-chip to unravel novel regulators and therapeutic targets in vascular diseases

V. Paloschi, J. Pauli, G. Winski, Z. Wu, Z. Li, N. Glukha, N. Hummel, R. Rogowitz, S. Meucci, L. Botti, A. Busch, E. Chernogubova, H. Jin, N. Sachs, H.-H. Eckstein, , L. Maegdefessel

The paper develops an artery-on-a-chip model to study shear stress effects on vascular diseases and identifies novel therapeutic targets.

bioRxiv · Nov 29, 2022 · PreprintCell Biology

Long-term expanding human airway organoids for disease modelling.

N. Sachs, D. D. Zomer-van Ommen, A. Papaspyropoulos, I. Heo, L. Bottinger, D. Klay, F. Weeber, G. Huelsz-Prince, N. Iakobachvili, M. C. Viveen, A. Lyubimova, L. Teeven, S. Derakhshan, J. Korving, H. Begthel, , H. Clevers

This study establishes long-term-expanding human airway organoids from broncho-alveolar biopsies or lavage material, enabling disease modeling of cystic fibrosis, lung cancer, and RSV infection.

bioRxiv · May 9, 2018Cell Biology