Author

N. Vandergrift

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

C. S. Nelson· 3 shared S. R. Permar· 3 shared K. Koelle· 2 shared A. Deshpande· 1 shared A. Kaur· 1 shared D. J. Diamond· 1 shared D. Tran· 1 shared D. V. Cruz· 1 shared

Activity by Year

2017-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

C. S. Nelson

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3 papers

Recent·Most cited

Genetic signatures of human cytomegalovirus variants acquired by seronegative glycoprotein B vaccinees

C. S. Nelson, D. Vera Cruz, M. Su, G. Xie, N. Vandergrift, R. Pass, M. Forman, M. Diener-West, K. Koelle, R. Arav-Boger, S. R. Permar

This paper analyzes the genetic composition of HCMV variants in gB vaccinees and placebo recipients, finding reduced viral shedding and altered viral population dynamics in vaccinated individuals.

bioRxiv · Oct 2, 2018Microbiology

HCMV glycoprotein B subunit vaccine efficacy was mediated by non-neutralizing antibody effector functions

C. S. Nelson, T. Huffman, E. Cisneros de la Rosa, G. Xi, N. Vandergrift, R. F. Pass, J. Pollara, S. R. Permar

This paper shows that the HCMV gB/MF59 vaccine's 50% efficacy is due to non-neutralizing antibodies that mediate virion phagocytosis, not neutralization.

bioRxiv · Jan 11, 2018Immunology

Preexisting antibodies can protect against congenital cytomegalovirus infection in monkeys

C. S. Nelson, D. V. Cruz, D. Tran, K. M. Bialas, L. Stamper, H. Wu, M. Gilbert, R. Blair, X. Alvarez, H. Itell, M. Chen, A. Deshpande, F. Chiuppesi, F. Wussow, D. J. Diamond, , S. R. Permar

This study shows that preexisting antibodies can prevent congenital cytomegalovirus infection in monkeys by blocking placental transmission.

bioRxiv · Apr 15, 2017Immunology