Author

O. MacLean

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Organism:chicken / avian· 1 Assay:clinical cohort / trial· 1 Research Focus:drug response / drug discovery· 1 Research Focus:genome assembly· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

M. Palmarini· 3 shared A. Taggart· 2 shared M. Stewart· 2 shared Q. Gu· 2 shared R. M. Pinto· 2 shared W. Furnon· 2 shared A. Cocco· 1 shared A. D. S. Filipe· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

M. Palmarini

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A Machine Learning Framework to Identify the Correlates of Disease Severity in Acute Arbovirus Infection

V. Herder, M. Caporale, O. MacLean, D. Pintus, X. Huang, K. Nomikou, N. Palmalux, J. Nichols, R. Scivoli, C. Boutell, A. Taggart, J. Allan, H. Malik, G. Ilia, Q. Gu, , M. Palmarini

This study uses machine learning to identify key viral and host processes associated with varying severity in bluetongue virus infection in sheep.

bioRxiv · Feb 23, 2024 · PreprintMicrobiology

Timing and magnitude of the type-I interferon response are determinants of disease tolerance in arbovirus infection

A. Hardy, S. Bakshi, W. Furnon, O. MacLean, Q. Gu, M. Varjak, M. Varela, M. A. Aziz, A. Shaw, R. M. Pinto, N. C. Ruiz, C. Mullan, A. Taggart, A. Filipe, R. E. Randall, , M. Palmarini

This study shows that the timing and magnitude of the type-I interferon response determine disease tolerance in bluetongue virus infection between sheep and cattle.

bioRxiv · Oct 19, 2022 · PreprintMicrobiology

In vitro evolution of Remdesivir resistance reveals genome plasticity of SARS-CoV-2

A. M. Szemiel, A. Merits, R. J. Orton, O. MacLean, A. Wickenhagen, G. Lieber, R. M. Pinto, M. L. Turnbull, S. Wang, D. Mair, A. da Silva Filipe, B. J. Willett, S. J. Wilson, A. H. Patel, E. C. Thomson, , M. E. Stewart

This study shows that in vitro evolution of SARS-CoV-2 under remdesivir selects for resistant mutations, but these mutations do not spread widely in global variants.

bioRxiv · Feb 1, 2021Microbiology