Author

M. Varjak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:Arabidopsis· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. Taggart· 2 shared E. Pondeville· 2 shared M. Palmarini· 2 shared M. Varela· 2 shared Q. Gu· 2 shared R. M. Pinto· 2 shared S. Bakshi· 2 shared S. Terry· 2 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

A. Taggart

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Timing and magnitude of the type-I interferon response are determinants of disease tolerance in arbovirus infection

A. Hardy, S. Bakshi, W. Furnon, O. MacLean, Q. Gu, M. Varjak, M. Varela, M. A. Aziz, A. Shaw, R. M. Pinto, N. C. Ruiz, C. Mullan, A. Taggart, A. Filipe, R. E. Randall, , M. Palmarini

This study shows that the timing and magnitude of the type-I interferon response determine disease tolerance in bluetongue virus infection between sheep and cattle.

bioRxiv · Oct 19, 2022 · PreprintMicrobiology

Zoonotic avian influenza viruses evade human BTN3A3 restriction

R. M. Pinto, S. Bakshi, S. Lytras, M. K. Zakaria, S. Swingler, J. C. Worrell, V. Herder, M. Varjak, N. Cameron-Ruiz, M. Collados-Rodriguez, M. Varela, A. Wickenhagen, C. Loney, Y. Pei, J. Hughes, , M. Palmarini

This study identifies BTN3A3 as a human restriction factor that inhibits avian influenza viruses but not human IAVs, with resistance linked to specific NP mutations.

bioRxiv · Jun 14, 2022 · PreprintMicrobiology

Mosquito saliva sialokinin-dependent enhancement of arbovirus infection through endothelial barrier leakage

D. Lefteri, S. Bryden, M. Pingen, S. Terry, E. Beswick, G. Georgiev, M. Van Der Laan, V. Mastrullo, P. Campagnolo, R. M. Waterhouse, M. Varjak, A. Merits, R. Fragkoudis, S. Griffin, E. Pondeville, C. S. McKimmie

This study identifies sialokinin in Aedes mosquito saliva as a factor that enhances arbovirus infection by reducing endothelial barrier integrity, suggesting it as a therapeutic target.

bioRxiv · Feb 19, 2021Microbiology

Sugar feeding enhances gut immunity and protects against arboviral infection in the mosquito vector Aedes aegypti

F. Almire, S. Terry, M. McFarlane, A. Szemiel, S. Terhzaz, M. Varjak, A. McDonald, A. Kohl, E. Pondeville

This study shows that sugar feeding enhances antiviral immunity in Aedes aegypti mosquitoes, reducing arbovirus transmission potential.

bioRxiv · Jan 5, 2021Physiology