Author

O. Ogoke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:imaging· 1

Frequent Co-Authors

N. Parashurama· 3 shared A. Chiang· 2 shared A. Kalinousky· 2 shared C. Ott· 2 shared C. Shamul· 2 shared D. Guiggey· 2 shared P. Chen· 2 shared S. Ross· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersBioengineering

N. Parashurama

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Author profile →

3 papers

Recent·Most cited

Linking collective migration/growth to differentiation boosts global shaping of the transcriptome and exhibits a grasshopper effect for driving maturation

O. Ogoke, D. Guiggey, A. Chiang, S. Thompson, T. H. A. Nguyen, D. Berke, C. Ott, A. Kalinousky, C. Shamul, P. Chen, S. Ross, Z. Chen, P. Srivastava, C. Gaughan, S. D. Mahajan, , N. Parashurama

The paper links collective migration to differentiation in hPSC-derived hepatocytes, showing a significant increase in maturation through a deep-learning gene circuit.

bioRxiv · Jul 24, 2022 · PreprintBioengineering

Mesenchyme modulates three-dimensional, collective cell migration of liver cells in vitro - a role for TGFβ pathway

O. Ogoke, O. Yousef, C. Ott, A. Kalinousky, L. Wayne, C. Shamul, S. Ross, N. Parashurama

This study develops 3D in vitro models of liver organogenesis to study collective cell migration, showing that mesenchyme modulates migration through TGFβ signaling and branching morphogenesis.

bioRxiv · Sep 27, 2020 · PreprintCell Biology

FOXA1/2 depletion drives global reprogramming of differentiation state and metabolism in a human liver cell line and inhibits differentiation of human stem cell-derived hepatic progenitor cells

I. T. Warren, D. Guiggey, A. Chiang, M. H. Maloy, O. Ogoke, T. S. Groth, T. Mon, S. Meamardoost, X. Liu, S. Thompson, A. Szeglowski, R. Thompson, P. Chen, R. Paulmurugan, M. L. Yarmush, , N. Parashurama

This study shows that depletion of FOXA1/2 in human liver cells reprograms differentiation state and metabolism, promoting de-differentiation and pluripotency.

bioRxiv · Jun 1, 2020Bioengineering