Defining T cell receptor repertoires using nanovial-based affinity and functional screening
D. Koo, Z. Mao, R. Dimatteo, N. Tsubamoto, M. Noguchi, J. McLaughlin, W. Tran, S. Lee, D. Cheng, J. de Rutte, G. Burton Sojo, O. Witte, D. Di Carlo
This study uses nanovials to screen antigen-specific T cells based on affinity and function, identifying a more specific functional TCR repertoire than standard techniques.
bioRxiv · Jan 17, 2023 · PreprintBioengineering