Author

J. Freeland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1

Frequent Co-Authors

M. Ruiz· 2 shared T. Graeber· 2 shared Y. Wang· 2 shared A. A. Sadoon· 1 shared C.-C. Chen· 1 shared D. Cheng· 1 shared D. Shackelford· 1 shared E. O'Donnell· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiophysics

M. Ruiz

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Author profile →

4 papers

Recent·Most cited

PGC-1a drives small cell neuroendocrine cancer progression towards an ASCL1-expressing subtype with increased mitochondrial capacity

G. Varuzhanyan, C.-C. Chen, J. Freeland, T. He, W. Tran, K. Song, L. Wang, D. Cheng, S. Xu, G. A. Dibernardo, F. N. Esedebe, V. Bhatia, M. Han, E. R. Abt, J. W. Park, , O. N. Witte

bioRxiv · Apr 9, 2024Cancer Biology

Genetic Screen in a Pre-Clinical Model of High-Grade Complex Karyotype Sarcoma Characterizes Drivers of Distinct Sarcoma Subtypes and Identifies New Therapeutic Vulnerabilities

M. A. Munoz, J. Freeland, E. O'Donnell, J. Langerman, J. Bergonio, J. Surarez-Navarro, M. Darrow, S. Thorpe, R. Randall, K. L. Carraway, O. Witte, T. Graeber, J. Carr-Ascher

This paper develops a pre-clinical model of high-grade complex karyotype sarcomas to identify subtype-specific drivers and therapeutic targets through genetic screening and transcriptomic analysis.

bioRxiv · Jun 13, 2022 · PreprintCancer Biology

Bent DNA bows as amplifiers and biosensors for detecting DNA-interacting salts and molecules

J. Freeland, L. Zhang, S.-T. Wang, M. Ruiz, Y. Wang

This study develops bent DNA bows to amplify and detect DNA interactions with salts and molecules, enabling sensitive and cost-effective analysis using gel electrophoresis and the modified Hill equation.

Sensors · May 31, 2020Peer-reviewedBiophysics

Faster diffusive dynamics of histone-like nucleoid structuring proteins in live bacteria caused by silver ions

A. A. Sadoon, P. Khadka, J. Freeland, R. K. Gundampati, R. Manso, M. Ruiz, V. R. Krishnamurthi, S. K. Thallapuranam, J. Chen, Y. Wang

This study shows that silver ions increase the diffusive motion of H-NS proteins in live bacteria by weakening their DNA binding through DNA dehybridization.

bioRxiv · Sep 30, 2019Biophysics