Author

M. Darrow

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Moores· 1 shared B. Bateman· 1 shared C. Spindloe· 1 shared D. Clarke· 1 shared D. J. Wright· 1 shared D. Kontziampasis· 1 shared D. Monteiro· 1 shared D. P. Klebl· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBiophysics

A. Moores

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Genetic Screen in a Pre-Clinical Model of High-Grade Complex Karyotype Sarcoma Characterizes Drivers of Distinct Sarcoma Subtypes and Identifies New Therapeutic Vulnerabilities

M. A. Munoz, J. Freeland, E. O'Donnell, J. Langerman, J. Bergonio, J. Surarez-Navarro, M. Darrow, S. Thorpe, R. Randall, K. L. Carraway, O. Witte, T. Graeber, J. Carr-Ascher

This paper develops a pre-clinical model of high-grade complex karyotype sarcomas to identify subtype-specific drivers and therapeutic targets through genetic screening and transcriptomic analysis.

bioRxiv · Jun 13, 2022 · PreprintCancer Biology

A massively multi-scale approach to characterising tissue architecture by synchrotron micro-CT applied to the human placenta

W. M. Tun, G. Poologasundarampillai, H. Bischof, G. Nye, O. N. F. King, M. Basham, Y. Tokudome, R. M. Lewis, E. D. Johnstone, P. Brownbill, M. Darrow, I. L. Chernyavsky

This study uses synchrotron micro-CT and machine learning to analyze placental tissue structure across scales, quantifying scale-dependent errors and enabling functional analysis of maternal and fetal domains.

bioRxiv · Dec 7, 2020Bioengineering

Need for speed: Examining protein behaviour during cryoEM grid preparation at different timescales

D. P. Klebl, M. S. C. Gravett, D. Kontziampasis, D. J. Wright, R. S. Bon, D. Monteiro, M. Trebbin, F. Sobott, H. D. White, M. Darrow, R. F. Thompson, s. P. muench

This study examines how different macromolecular complexes behave during cryoEM grid preparation at various timescales using three vitrification devices.

bioRxiv · May 14, 2020Biochemistry

Solid immersion microscopy readily and inexpensively enables 12 nm resolution on plunge-frozen cells

M. L. Martin-Fernandez, L. Wang, B. Bateman, L. C. Zanetti-Domingues, A. Moores, S. R. Needham, D. Rolfe, S. Astbury, C. Spindloe, M. Darrow, M. Romano, K. Beis, D. Clarke

This paper introduces a low-cost solid immersion lens technique that achieves 12 nm resolution in cryogenic fluorescence microscopy, outperforming more expensive systems.

bioRxiv · Jul 20, 2018 · PreprintBiophysics