Cell BiologybioRxiv
Adult Stem Cell-derived Complete Lung Organoid Models Emulate Lung Disease in COVID-19
C. Tindle, M. Fuller, A. Fonseca…·S. Das
This study develops a human lung organoid model to emulate COVID-19 pathogenesis, showing proximal airway cells drive viral infection while distal cells drive excessive immune response.
DOI 10.7554/elife.66417