Author

P. Dhavarasa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Dvorkin-Gheva· 1 shared B. G. Wouters· 1 shared D. Hedley· 1 shared D. Szames· 1 shared E. Mollen· 1 shared F. Jessa· 1 shared F. Notta· 1 shared G. H. Jang· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. Dvorkin-Gheva

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2 papers

Recent·Most cited

BiochemistrybioRxivOct 3, 2023

CRISPR Screening in Tandem with Targeted mtDNA Damage Reveals WRNIP1 Essentiality

T. Sack, P. Dhavarasa, D. Szames…·S. O. Kelley

The paper uses mtDNA-damaging agents and CRISPR screening to identify genes essential for mtDNA damage response, finding WRNIP1 essential for mtDNA repair and mitochondrial turnover.

DOI 10.1021/acschembio.3c00620

humangenetic perturbation / CRISPR

𝕏 PostBluesky

Cancer BiologybioRxivOct 8, 2020

NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4

P. Jain, A. Dvorkin-Gheva, E. Mollen…·M. Koritzinsky

This study identifies NOX4 as a link between metabolic deregulation and ER-specific redox vulnerability in PDAC, suggesting PRDX4 as a therapeutic target for pancreatic cancer.

DOI 10.1126/sciadv.abf7114

humanproteomics

𝕏 PostBluesky