PhysiologybioRxivPreprint
Lymph Nodes Inhibit T-cell Effector Functions Locally by Establishing Acidic Niches
H. Wu, V. Estrella, P. Enriquez-Navas…·r. gillies
The paper shows that acidic niches in lymph nodes inhibit T-cell effector functions by blocking lactic acid efflux and reducing glycolysis, keeping T-cells in a state of stasis.
DOI 10.1101/689604