Author

P. H. Herdewijn

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Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

A. K. Singh· 1 shared D. Schols· 1 shared H. Nguyen· 1 shared K. Das· 1 shared S. De Jonghe· 1 shared S. E. Martinez· 1 shared W. Gu· 1 shared

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2021-2021 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A. K. Singh

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1 paper

Recent·Most cited

BiophysicsbioRxivJul 3, 2021

Sliding of HIV-1 reverse transcriptase over DNA creates a transient P pocket - Targeting P-pocket by fragment screening

A. K. Singh, S. E. Martinez, W. Gu…·K. Das

The paper identifies a transient P-pocket in HIV-1 reverse transcriptase during DNA sliding and demonstrates fragment screening to target this pocket for inhibitor development.

DOI 10.1038/s41467-021-27409-y

virusstructural biology

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