Author

S. E. Martinez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:cryo-EM· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Organism:plant (other)· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

K. Das· 3 shared A. K. Singh· 2 shared B. De Wijngaert· 2 shared D. Schols· 2 shared H. Nguyen· 2 shared A. M. Guercio· 1 shared C. Dharia· 1 shared C. E. Conn· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersBiophysics

K. Das

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cryo-EM structures of Doravirine and Rilpivirine with HIV-1 Reverse Transcriptase/DNA Aptamer: Nonnucleoside Inhibitor Resistance by E138K and M184I Mutations

A. K. Singh, B. De Wijngaert, M. Bijnens, K. Uyttersprot, H. Nguyen, S. E. Martinez, D. Schols, P. Herdewijn, C. Pannecouque, E. Arnold, K. Das

The paper determines cryo-EM structures of HIV-1 reverse transcriptase with nonnucleoside inhibitors, revealing structural changes due to resistance mutations.

bioRxiv · Feb 27, 2022 · PreprintBiophysics

A KARRIKIN INSENSITIVE2 paralog in lettuce mediates highly sensitive germination responses to karrikinolide

S. E. Martinez, C. E. Conn, A. M. Guercio, C. Sepulveda, C. J. Fiscus, D. Koenig, N. Shabek, D. C. Nelson

This study identifies LsKAI2b as the lettuce receptor mediating sensitive KAR1 germination responses, with specific residues determining ligand specificity.

bioRxiv · Oct 13, 2021Plant Biology

Sliding of HIV-1 reverse transcriptase over DNA creates a transient P pocket - Targeting P-pocket by fragment screening

A. K. Singh, S. E. Martinez, W. Gu, H. Nguyen, D. Schols, P. H. Herdewijn, S. De Jonghe, K. Das

The paper identifies a transient P-pocket in HIV-1 reverse transcriptase during DNA sliding and demonstrates fragment screening to target this pocket for inhibitor development.

bioRxiv · Jul 3, 2021Biophysics

Cryo-EM structures reveal transcription initiation steps by yeast mitochondrial RNA polymerase

B. De Wijngaert, S. Sultana, C. Dharia, H. Vanbuel, J. Shen, D. vasilchuk, S. E. Martinez, E. Kandiah, S. S. Patel, K. Das

The paper uses cryo-EM to reveal steps of transcription initiation by yeast mitochondrial RNA polymerase, including promoter melting, template alignment, and abortive synthesis mechanisms.

bioRxiv · Apr 13, 2020Biophysics