Author

P. Ilinykh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Assay:cryo-EM· 1 Organism:human· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

A. Bukreyev· 2 shared A. B. Ward· 1 shared A. I. Flyak· 1 shared A. L. Brunh· 1 shared B. Doranz· 1 shared C. D. Murin· 1 shared C. Ye· 1 shared E. Davidson· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

A. Bukreyev

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2 papers

Recent·Most cited

Multiple layers of innate immune response antagonism of SARS-CoV-2

F. Zhou, S. Periasamy, N. Jackson, W. S. Cheng, R. Soto Acosta, P. Ilinykh, C. Ye, S. Chauhan, G. Nudelman, E. Zaslavsky, S. Widen, L. Martinez-Sobrido, S. Sealfon, A. Bukreyev

This study generates twelve SARS-CoV-2 viruses with mutations in individual proteins and shows that many have interferon-antagonizing activity and immunosuppressive effects in human cells and mice, with NSP1 and NSP15 having the greatest impact.

bioRxiv · Jan 29, 2024 · PreprintMicrobiology

Convergence of a common solution to broad ebolavirus neutralization by glycan cap directed human antibodies

C. D. Murin, P. Gilchuk, P. Ilinykh, K. Huang, N. Kuzmina, X. Shen, J. F. Brunh, A. L. Brunh, E. Davidson, B. Doranz, L. E. Williamson, J. Copps, T. Alkutkar, A. I. Flyak, A. Bukreyev, , A. B. Ward

The paper presents cryo-EM structures of glycan cap antibodies that neutralize ebolavirus by targeting a conserved MLD-anchor site, revealing common features among broadly neutralizing antibodies.

bioRxiv · Oct 14, 2020Immunology